Now at Penn: Gamma Knife® Perfexion™

Gamma Knife® Perfexion™ is the latest form of precision radiation therapy for treating cancer. This non-surgical treatment uses 192 sources of radiation to precisely target tumors, lesions and other intracranial structures.
Radiation therapy damages cancer cells and tumors, preventing them from multiplying. The Gamma Knife was developed in 1968 and primarily used to treat intractable pain and movement disorders. Compared with earlier Gamma Knife versions, Perfexion offers an expanded reach for treating metastasis anywhere in the brain and can also treat multiple locations in a single session.
Gamma Knife® Perfexion™ is one of a full range of treatment options for benign, malignant and metastatic cancer that Penn Medicine offers patients in the Philadelphia region. Currently, Penn Neurosurgery treats as many as 300 patients in the Penn Gamma Knife Center—the most of any hospital in the Philadelphia region.

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• Gamma Knife® Perfexion™
• Penn Neuro Surgery

The Penn Gamma Knife® Center -- Blade-Free Brain Surgery

Gamma Knife radiosurgery is a powerful and precise surgical option for patients suffering from brain tumors and other serious brain disorders. The technique is non-invasive, effective, safe and does not require an incision, making it the optimal treatment for a wide variety of conditions including benign and malignant brain tumors, blood vessel malformations, trigeminal neuralgia and tremor. The Penn Gamma Knife Center at Pennsylvania Hospital, Philadelphia's regional leader in Gamma Knife radiosurgery, recently celebrated its fourth anniversary. In addition, Penn Neurology and Neurosurgery at the Hospital of the University of Pennsylvania (HUP) are now ranked 15th in the United States by U.S.News & World Report. They are the only neuroscience programs in the region to be recognized. Learn More